# ToxIndex > Agentic computational toxicology platform that turns curated data, validated tools, and a regulatory document index into citable, reproducible chemical safety assessments. Built by Insilica Inc. ToxIndex compresses chemical safety assessment from months to hours, and every finding traces back to its source. This file indexes the site for agents and LLMs. Links point to pages on https://toxindex.com. ## Start here - [Platform overview](https://toxindex.com/platform): The whole platform — Sage and Flow over a foundation of curated data, tools, and regulatory evidence. - [Solutions](https://toxindex.com/solutions): Ways in by the assessment you owe, the industry you work in, or the team you sit on. - [Pricing](https://toxindex.com/pricing): Plans and what each one includes. - [Trust & security](https://toxindex.com/trust): Security posture, deployment models, and how chemical data is handled. - [Docs](https://toxindex.com/docs): Product documentation — getting started, platform overview, and reproducibility. - [Contact / book a demo](https://toxindex.com/contact): Talk to the team or book a demo. - [Try it free (app)](https://platform.toxindex.com): Free, limited-access version of ToxIndex — Sage, ToxJobs, Kiln, and Crawler. The rest of the suite is being released publicly over time; the full platform is shown in demos. ## Platform ### Interfaces Ask a question and get a cited answer, or run a workflow that produces the same result every time. Both sit on top of the same evidence. - [Sage](https://toxindex.com/platform/sage): Sage, ToxIndex's conversational agent, gives natural-language, cited answers over curated toxicology data, regulatory documents, and live predictions. - [Flow](https://toxindex.com/platform/flow): Flow, ToxIndex's reproducible AI workflow engine, runs ontology-driven templates with versioned provenance and a full audit trail on every run. ### Data & knowledge Curated databases, a global regulatory document index, and authoritative chemical lists — cross-linked and traceable to source. - [Kiln](https://toxindex.com/platform/kiln): Kiln is ToxIndex's curated database layer, resolving 356 toxicology and chemistry databases into 2.8B cross-linked data points. - [Yard](https://toxindex.com/platform/yard): Yard, ToxIndex's raw data warehouse, assembles 2,000+ integrated databases into a knowledge graph of 100B+ data points. - [Crawler](https://toxindex.com/platform/crawler): Crawler, ToxIndex's regulatory document search engine, indexes 114M+ documents from 1,000+ sources across 80+ curated collections. - [Lists](https://toxindex.com/platform/lists): Lists tracks 53,842 chemicals across 20 regulatory lists and 7 jurisdictions, under a strict authoritative-source-only policy. - [Ontology](https://toxindex.com/platform/ontology): The ToxIndex ontology is a permissively licensed, actively maintained domain ontology that makes the platform interoperable with the semantic web. ### Prediction & modeling Run 150+ validated tools, OECD read-across, and in-house transformer models when a study does not exist, then see exactly where the number came from. - [ToxJobs](https://toxindex.com/platform/toxjobs): ToxJobs is ToxIndex's prediction toolkit: 150+ deployed toxicology tools and the automated OECD QSAR Toolbox 4.8, all behind one uniform, continuously monitored API. - [Gaps](https://toxindex.com/platform/gaps): Gaps ingests IUCLID dossiers, maps studies to endpoints, and flags missing data automatically, backed by the Yard warehouse. - [ToxTransformer](https://toxindex.com/platform/toxtransformer): ToxTransformer is ToxIndex's open-source molecular toxicity model, predicting 6,647 endpoints from chemical structure. Inspect it, run it, and extend it on GitHub. - [Pleiome](https://toxindex.com/platform/pleiome): Pleiome is ToxIndex's generative multi-property transformer, predicting 150,000+ endpoints at once and running inverse design to hit a target safety profile. ## Solutions ### By job to be done Start from the deliverable you owe a regulator or a colleague: a registration, a new-chemical hazard picture, an impurity call, a gap analysis, a screen. - [REACH registration](https://toxindex.com/solutions/reach-compliance): ToxIndex compresses REACH registration by gathering known hazard data, running OECD read-across, and mapping dossiers to endpoints with a full provenance trail. - [New chemical assessment](https://toxindex.com/solutions/new-chemical-assessment): ToxIndex characterizes a novel chemical from its structure alone, combining predictive models, mechanistic analog identification, and read-across with a full audit trail. - [ICH M7 impurity assessment](https://toxindex.com/solutions/ich-m7-mutagenic-impurities): ToxIndex runs ICH M7 mutagenic-impurity assessments as reproducible workflows, pairing structural-alert profiling with bacterial mutagenicity prediction and a full audit trail. - [Data gap analysis](https://toxindex.com/solutions/data-gap-analysis): ToxIndex automates data-gap analysis by ingesting IUCLID dossiers, mapping studies to toxicology endpoints, and flagging genuine gaps against a knowledge warehouse. - [Consumer product screening](https://toxindex.com/solutions/consumer-product-safety): ToxIndex screens consumer-product ingredients at scale, running batch hazard checks and multi-jurisdiction restriction checks with plain-language, cited answers. ### By industry Every sector answers to a different set of frameworks and lists. Pick yours and see the coverage that applies. - [Pharmaceuticals](https://toxindex.com/solutions/pharmaceuticals): ToxIndex gives pharma teams reproducible ICH M7 impurity assessments, structure-based safety prediction, and cited answers backed by a full audit trail. - [Cosmetics & personal care](https://toxindex.com/solutions/cosmetics): ToxIndex screens cosmetics ingredients across jurisdictions, covers SCCS and CosIng, and warns early when a restriction changes. - [Agriculture & crop protection](https://toxindex.com/solutions/agriculture): ToxIndex covers mammalian and eco endpoints for agricultural actives and their metabolites, with read-across and reproducible assessments. - [Chemicals & energy](https://toxindex.com/solutions/chemicals-energy): ToxIndex brings portfolio-scale REACH and TSCA support to chemicals and energy, with read-across, gap analysis, and reproducible product stewardship. - [Consumer products](https://toxindex.com/solutions/consumer-products): ToxIndex speeds consumer-product development with early-stage ingredient screening, multi-market restriction checks, and plain-language safety answers. ### By team A CRO, a consultancy, and an internal safety group each buy for a different reason. Find the fit that matches how your work gets paid for. - [CROs](https://toxindex.com/solutions/cros): ToxIndex raises throughput per toxicologist at a CRO, automating data gathering and prediction to produce reproducible, client-ready deliverables. - [Consultancies](https://toxindex.com/solutions/consultancies): ToxIndex gives consultancies coverage across frameworks, reproducible deliverables, and evidence trails that stand up to regulatory scrutiny. - [Internal safety teams](https://toxindex.com/solutions/internal-safety-teams): ToxIndex extends a lean in-house safety team with automated screening, reproducible assessments, and self-serve answers for the wider org. ## Resources - [Research](https://toxindex.com/research): Peer-reviewed papers behind the platform. - [Reports](https://toxindex.com/reports): Sample assessments you can read end to end. - [Compare](https://toxindex.com/compare): How ToxIndex compares to legacy platforms and manual review. ## Company - [About](https://toxindex.com/about): The company and team behind ToxIndex. - [Contact](https://toxindex.com/contact): Get in touch. ## Machine-readable surfaces - Clean-markdown version of any platform, solution, docs, or compare page: append `.md` to its URL (e.g. https://toxindex.com/platform/sage.md, https://toxindex.com/solutions/reach-compliance.md, https://toxindex.com/docs/getting-started.md). - Regulatory chemical lists: https://lists.toxindex.com - ToxIndex ontology (v1): https://ontology.toxindex.com/v1 - Sitemap: https://toxindex.com/sitemap-index.xml ## About ToxIndex ToxIndex is built by Insilica Inc., a Maryland-based AI toxicology company in the BioHealth Capital Region that has built AI for scientific data curation and evidence review for over a decade. Its earlier platforms, BioBricks.ai and Sysrev.com, are peer-reviewed and in public use. Insilica's work is backed by NIH/NIEHS, NSF, and EU (ONTOX) research funding, and it develops three of the ONTOX consortium's core AI tools. The security posture aligns with SOC 2, with audits in progress; see the Trust Center at https://trust.insilica.co. Founder and CEO: Dr. Tom Luechtefeld.