Building the infrastructure for computational toxicology
Toxicologists spend most of their time gathering evidence, not evaluating it. We've spent years (backed by NIH, NSF, and EU Horizon grants) building tools that automate the gathering, prediction, and report generation so they can focus on the science.
ToxIndex is operated by Insilica, a team of data scientists, computational researchers, and software engineers.
Our Approach
Our approach
Domain-specific AI
Models trained on toxicology data, regulatory language, and chemical safety workflows. Not general-purpose AI with a science prompt. These are tools we built from scratch for computational toxicology.
Open data foundation
A curated knowledge graph linking hundreds of chemistry and toxicology datasets into one queryable structure. Selected by NSF for the Proto-OKN initiative to build the first national open knowledge network for chemical safety.
Human-in-the-loop
Assessments go through expert review. Toxicologists validate conclusions, catch errors, and build the audit trails that regulatory submissions require. The AI handles evidence gathering; the scientist handles judgment.
Regulatory alignment
FDA Modernization Act 2.0 removed mandatory animal testing. NIH no longer funds animal-only research. REACH and SCCS increasingly require New Approach Methodologies. ToxIndex is the infrastructure these regulations need.
Research
Research funding
Federal and international grants funding core platform development.
| Award | Project | Year |
|---|---|---|
| NIH SBIR | srvc-EHSR | 2025 |
| NIH SBIR | BioBricks Environmental Health | 2024 |
| NIH SBIR | Sysrev | 2024 |
| NSF Proto-OKN | BioBricks OKN | 2023 |
| NIH SBIR | ToxIndex-CPG | 2022 |
| EU Horizon | ONTOX | 2021 |
Security
Security
SOC 2 aligned
Controls across the platform
Encrypted everywhere
At rest and in transit
Audit logging
Role-based access, every action recorded
Your data stays yours
Never used to train models, never shared across workspaces
Continuous scanning
Vulnerability scanning and dependency auditing
Tenant isolation
No cross-tenant access, period
See it in action
We'll walk you through a live assessment on your substances.