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Characterize actives and metabolites with mammalian and eco endpoints in one place.
Crop-protection registration spans mammalian toxicology, ecotoxicology, and environmental fate — for the active and its metabolites, under EU and international frameworks. ToxIndex pulls that breadth of evidence together and fills the endpoints without a study.
Updated July 18, 2026
- 356
- curated databases spanning tox and ecotox
- 57
- OECD QSAR Toolbox endpoints
- Reproducible
- against a versioned regulatory context
The situation
Breadth is the hard part
Agrochemical dossiers are wide: mammalian toxicology, ecotoxicology, and environmental fate, each with its own endpoints, across the active substance and its metabolites. Assembling that evidence from scattered sources is where the months go.
ToxIndex resolves each substance against a curated foundation that spans mammalian and ecotox data, runs predictors and read-across for the empty endpoints, and keeps every step reproducible against the regulatory context it ran under.
How ToxIndex helps
What ToxIndex covers for agriculture
Tox and ecotox in one foundation
Kiln resolves actives and metabolites against curated mammalian and ecotoxicology data, cross-linked and cited.
Fill wide endpoint sets
Predictors and OECD read-across cover the endpoints without a study, each with confidence and justification.
Track metabolites explicitly
The QSAR Toolbox simulates metabolic pathways, so metabolites are characterized rather than assumed away.
Reproducible dossiers
Flow versions the data snapshot and models, so an assessment reruns cleanly when guidance shifts.
The tools behind it
What runs underneath
FAQ
Questions teams ask
Frequently asked questions
Does ToxIndex cover both mammalian and eco endpoints?
Yes. Kiln resolves actives and metabolites against 356 curated databases spanning mammalian toxicology and ecotoxicology, cross-linked and cited.
How are metabolites handled?
The QSAR Toolbox simulates metabolic pathways and characterizes each metabolite explicitly.
How many endpoints does it cover?
Predictors and OECD read-across cover the 57 QSAR Toolbox endpoints for the studies you do not have.
See it on your own chemistry.
Try the free version now, or book a walkthrough of the full platform on your substances.